Endogenous Retrovirus Erv-3 Is Not Implicated in Rheumatoid Arthritis But

Endogenous retrovirus ERV-3 is not implicated in rheumatoid arthritis but may provide a biomarker for osteoarthritis.

The Journal of Rheumatology Volume 37, no. 2 May Provide a Biomarker for Osteoarthritis Endogenous Retrovirus Erv-3 Is Not Implicated in Rheumatoid Arthritis But

Viruses and lymphocytes in rheumatoid arthritis. II. Examination of lymphocytes and sera from patients with rheumatoid arthritis for evidence of retrovirus infection.

The possible involvement of retroviruses in the aetiology of rheumatoid arthritis (RA) was investigated. Retrovirus antigens were not expressed on rheumatoid synovial and peripheral blood lymphocytes as judged by membrane immunofluorescence, radioimmunoassay, and complement-mediated cytotoxicity. The specific antiretroviral (anti-RD-144 and anti-SSAV) sera used in this study were produced in ra...

Isolation and phylogeny of endogenous retrovirus sequences belonging to the HERV-W family in primates.

An investigation was undertaken of primate pol gene sequences from a novel endogenous retrovirus family, ERV-W, related to a new human endogenous retrovirus family (HERV-W) that includes multiple sclerosis-associated retrovirus (MSRV) sequences identified in particles recovered from monocyte cultures from patients with multiple sclerosis. The pol gene sequences of the ERV-W family were detected...

Placental endogenous retrovirus (ERV): structural, functional, and evolutionary significance.

That endogenous retrovirus (ERV) is present within the placenta of humans and other mammals has been known for the past 25 years, but the significance of this observation is still not fully understood. Much molecular biological data have emerged in recent years to support the earlier electron microscopic data on the presence of placental ERV. The evidence for ERV in animal and human placental t...